Download e-book for iPad: Alzheimer's disease and related disorders annual, 2002 by Jeffrey L Cummings, Serge Gauthier

By Jeffrey L Cummings, Serge Gauthier

ISBN-10: 1841842346

ISBN-13: 9781841842349

Given the advance of latest healing concepts and items, Serge Gauthier and Jeffrey Cummings have compiled a listing of latest subject matters in order to be of curiosity essentially to neurologists targeting Alzheimer's illness, and in addition to psychiatrists and geriatricians. The members, all revered of their subspecialties, have written updated, comprehensively referenced chapters which should supply information in addition to stimulate dialogue on the place present remedy is heading.

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Extra info for Alzheimer's disease and related disorders annual, 2002

Sample text

Amyloid beta vaccination: reduced plaques and improved cognition. Nat Med 2001; 7:18–19. 100. Vandermeeren M, Geraerts M, Pype S et al. The functional gamma-secretase inhibitor prevents production of amyloid beta 1–34 in human and murine cell lines. Neurosci Lett 2001; 315:145–148. 101. Shearman MS, Beher D, Clarke EE et al. L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid betaprotein precursor gammasecretase activity. Biochemistry 2000; 39:8698–8704. Alzheimers CH02 17/6/02 2:36 pm Page 37 References 102.

Brain Res 2001; 898:350–357. 34. Stefanis L, Park DS, Yan CY et al. Induction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis. J Biol Chem 1996; 271:30663– 30671. 35. Troy CM, Stefanis L, Greene LA, Shelanski ML. Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells. J Neurosci 1997; 17:1911– 1918. 36. Chan SL, Mattson MP. Caspase and calpain substrates: roles in synaptic plasticity and cell death.

87. Buttini M, Akeefe H, Lin C et al. Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease. Neuroscience 2000; 97:207–210. 88. Danik M, Poirier J. Apolipoprotein E and neuronal plasticity following experimental de-afferentation and in Alzheimer’s disease. Biochem Soc Trans 1998; 26:262–266. 89. Troy CM, Rabacchi SA, Xu Z et al. Beta-amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation. J Neurochem 2001; 77:157–164. 90.

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Alzheimer's disease and related disorders annual, 2002 by Jeffrey L Cummings, Serge Gauthier


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